Array
(
)
1
> Pathway Inhibitors>Enzyme Inhibitors>NF-κB>Kamebakaurin

NF-κB

Kamebakaurin View larger

Kamebakaurin

ATWS1977

CAS 73981-34-7

More details

1000 Items

Molarity Calculation Cart®

HOW TO ORDER

$85.00

$85.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $72.25 Total: $361.25
110 $61.20 Total: $612.00
125 $51.85 Total: $1,296.25
150 $44.20 Total: $2,210.00
1100 $38.25 Total: $3,825.00

Data sheet

Molecular FormulaC20H30O5
Molecular Weight350.45
CAS Numbers73981-34-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[H][C@@]1(O)[C@H]2CC[C@]3([H])[C@]1([C@H](O)C[C@]1([H])C(C)CC[C@H](O)[C@@]31CO)C(=O)C2=C
ReferencesWang K S , Lee J J . Kamebakaurin inhibits the expression of hypoxia-inducible factor-1? and its target genes to confer antitumor activity[J]. Oncology Reports, 2016, 35[4] 2045.

More info

1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1? and its target genes to confer antitumor activity. 3. Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-?B) p50.4. Kamebakaurin has anti-neuroinflammatory activity via inhibition of c-Jun NH -terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells.