NF-κB

Sanggenon C View larger

Sanggenon C

AT4S1615

CAS 80651-76-9

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$82.00

$82.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $36.90 Total: $3,690.00
150 $42.64 Total: $2,132.00
125 $50.02 Total: $1,250.50
110 $59.04 Total: $590.40
15 $69.70 Total: $348.50

Data sheet

Molecular FormulaC40H36O12
Molecular Weight708.71
CAS Numbers80651-76-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)=CC[C@]12Oc3cc(O)c([C@H]4C=C(C)C[C@@H]([C@H]4C(=O)c4ccc(O)cc4O)c4ccc(O)cc4O)c(O)c3C(=O)[C@@]1(O)Oc1cc(O)ccc21
ReferencesHuang H , Liu N , Zhao K , et al. Sanggenon C decreases tumor cell viability associated with proteasome inhibition[J]. Front Biosci, 2011, 3[4] 1315-1325.

More info

1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO production and iNOS expression by suppressing NF-?B activity and I?B? activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.