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View larger DP2392-E10
AOB11602
CAS: 340296-14-2
Chemical Name: Ethyl 5-(4-nitrophenyl)-4,6-dioxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $109.65 | Total: $548.25 |
| 1 | 10 | $92.88 | Total: $928.80 |
| 1 | 25 | $78.69 | Total: $1,967.25 |
| 1 | 50 | $67.08 | Total: $3,354.00 |
| 1 | 100 | $58.05 | Total: $5,805.00 |
Data sheet
| Molecular Formula | C14H10N4O6 |
| Molecular Weight | 330.26 |
| CAS Numbers | 340296-14-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | DP2392-E10; DP2392E10; DP2392 E10 |
| IUPAC/Chemical Name | Ethyl 5-(4-nitrophenyl)-4,6-dioxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate |
| InChl Key | KJAJWCHANQMLIT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C14H10N4O6/c1-2-24-14(21)11-9-10(15-16-11)13(20)17(12(9)19)7-3-5-8(6-4-7)18(22)23/h3-6H,2H2,1H3,(H,15,16) |
| SMILES Code | CCOC(=O)C1=C2C(=NN1)C(=O)N(C2=O)C3=CC=C(C=C3)[N+](=O)[O-] |
| References | 1) Alaa Shaikhqasem et al., Characterization of Inhibition Reveals Distinctive Properties for Human and Saccharomyces cerevisiae CRM1, J. Med. Chem. 2020, 63, 14, 7545–7558 2) Nopporn Chutiwitoonchai et al., Inhibition of CRM1-mediated nuclear export of influenza A nucleoprotein and nuclear export protein as a novel target for antiviral drug development, Virology. 2017 Jul; 507: 32–39. |
More info
Novel anti-influenza agent, inhibiting replication of a broad range of influenza A subtypes by inhibiting the nuclear export function of the viral nucleoprotein-nuclear export signal 3 (NP-NES3) domain