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View larger 6-Hydroxy-DOPA
AT26396
CAS 21373-30-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $32.30 | Total: $161.50 |
| 1 | 10 | $27.36 | Total: $273.60 |
| 1 | 25 | $23.18 | Total: $579.50 |
| 1 | 50 | $19.76 | Total: $988.00 |
| 1 | 100 | $17.10 | Total: $1,710.00 |
Data sheet
| Molecular Formula | C9H11NO5 |
| Molecular Weight | 213.19 |
| CAS Numbers | 21373-30-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(C(O)=O)N)C1=C(O)C=C(O)C(O)=C1 |
| References | Chandramouly G, McDevitt S, Sullivan K, Kent T, Luz A, Glickman JF, Andrake M, Skorski T, Pomerantz RT. Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. Chem Biol. 2015 Nov 19;22[11] 1491-1504. doi 10.1016j.chembiol.2015.10.003. Epub 2015 Nov 5. PubMed PMID 26548611; PubMed Central PMCID PMC4701204. |
More info
6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.