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Nuclear Receptor Ligands
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View larger ETP-45658
AT25399
CAS 1198357-79-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C16H17N5O2 |
| Molecular Weight | 311.34 |
| CAS Numbers | 1198357-79-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cn1ncc2c(nc(nc12)-c1cccc(O)c1)N1CCOCC1 |
| References | Maswadeh et al [2015] Coadministration of dox. and etop. loaded in camel milk phospholipids liposomes showed increased antitumor activity in a murine model. PLoS One 10 2847 PMID 25926730 |
More info
ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-K?, PI 3-K?, PI 3-K? and PI 3-K? respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively).