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View larger DDR1-IN-4
AT39572
CAS 2125676-13-1
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $155.55 | Total: $777.75 |
| 1 | 10 | $131.76 | Total: $1,317.60 |
| 1 | 25 | $111.63 | Total: $2,790.75 |
| 1 | 50 | $95.16 | Total: $4,758.00 |
| 1 | 100 | $82.35 | Total: $8,235.00 |
Data sheet
| Molecular Formula | C23H20BrF3N6O3 |
| Molecular Weight | 565.34 |
| CAS Numbers | 2125676-13-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(NCC(F)(F)F)CN1C(=O)C2(C=3C(Br)=CC=CC31)CCN(C(=O)C4=NC=5C=NNC5C=C4)CC2 |
| References | Hans Richter, et al. DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome. ACS Chem Biol. 2019 Jan 18;14[1] 37-49. |
More info
DDR1-IN-4 (Compound 2.45) is a highly potent inhibitor that selectively targets Discoidin Domain Receptor 1 (DDR1) autophosphorylation, demonstrating exceptional efficacy with IC50 values of 29 nM for DDR1 and 1.9 ?M for DDR2.