Nuclear Receptor Ligands

Pyridostatin TFA View larger

Pyridostatin TFA

AT4470

CAS 1472611-44-1

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$28.00

$28.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.60 Total: $1,260.00
150 $14.56 Total: $728.00
125 $17.08 Total: $427.00
110 $20.16 Total: $201.60
15 $23.80 Total: $119.00

Data sheet

Molecular FormulaC37H35F9N8O11
Molecular Weight938.71
CAS Numbers1472611-44-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)C(F)(F)F.NCCOc1cc(nc(c1)C(=O)Nc1cc(OCCN)c2ccccc2n1)C(=O)Nc1cc(OCCN)c2ccccc2n1
ReferencesKoirala D,etal.A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands.Nat Chem. 2011 Aug 28;3[10] 782-7.

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Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.