Nuclear Receptor Ligands

DNA polymerase-IN-1 View larger

DNA polymerase-IN-1

AT80644

CAS 809234-33-1

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$166.00

$166.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $74.70 Total: $7,470.00
150 $86.32 Total: $4,316.00
125 $101.26 Total: $2,531.50
110 $119.52 Total: $1,195.20
15 $141.10 Total: $705.50

Data sheet

Molecular FormulaC10H7ClO4
Molecular Weight226.61
CAS Numbers809234-33-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1OC=2C=C(O)C=C(O)C2C(=C1)CCl
ReferencesBruna-Haupt EF, et al. Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents. ACS Omega. 2023 Jul 13;8[29] 26479-26496.

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DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 ?M. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an IC50 of less than 250 ?M. DNA polymerase-IN-1 was shown to inhibit Taq DNA polymerase by RT- DNA polymerase-IN-1 showed antiretroviral activity in vitro by RT-PCR assay and can be used to study oxidative damage and colorectal cancer.