Nuclear Receptor Ligands

KCC-07 View larger

KCC-07

AT8554

CAS 315702-75-1

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$29.00

$29.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.05 Total: $1,305.00
150 $15.08 Total: $754.00
125 $17.69 Total: $442.25
110 $20.88 Total: $208.80
15 $24.65 Total: $123.25

Data sheet

Molecular FormulaC14H11N3OS
Molecular Weight269.32
CAS Numbers315702-75-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC1=CC=CC(NC2=NC(=CS2)C2=NC=CC=C2)=C1
ReferencesDan Zhu, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 From Mdm2-Mediated Degradation. Cancer Cell. 2018 Jun 11;33[6] 1004-1016.e5.

More info

KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1p53p21 signaling.