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View larger Mtb ATP synthase-IN-1
AT60877
CAS 2642394-38-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Data sheet
| Molecular Formula | C17H13N3O4 |
| Molecular Weight | 323.3 |
| CAS Numbers | 2642394-38-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C(=O)C(NCC2=NC=CC=C2)=C1NC3=CC=C4OCOC4=C3 |
| References | Li P, et al. Design, synthesis and biological evaluation of diamino substituted cyclobut-3-ene-1,2-dione derivatives for the treatment of drug-resistant tuberculosis. Eur J Med Chem. 2020;206 112538. |
More info
Mtb ATP synthase-IN-1 (compound 6ab) is a potent inhibitor of Mycobacterium tuberculosis (Mtb) ATP synthase (MIC = 0.452-0.499 ?gmL) [1] that can be used in anti-mycobacterium research, showing low cytotoxicity (Vero IC 50 > 64 ?gmL) and acceptable oral bioavailability with good metabolic stability.