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> Pathway Inhibitors>Enzyme Inhibitors>p38>(-)-Bornyl acetate

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(-)-Bornyl acetate View larger

(-)-Bornyl acetate

ATN1448

CAS 5655-61-8

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Data sheet

Molecular FormulaC12H20O2
Molecular Weight196.29
CAS Numbers5655-61-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@]12[C@H](OC(C)=O)C[C@@](C1(C)C)(CC2)[H]
ReferencesChen N, et al. Inhibition of lung inflammatory responses by bornyl acetate is correlated with regulation of myeloperoxidase activity. J Surg Res. 2014 Jan;186[1] 436-4

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(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. Isolated from hyssop oil, it possesses antifungal, highly active whitening, and antioxidant properties, and it has potential applications in cosmeceutical materials. It downregulates proinflammatory cytokines in vitro and in vivo, reduces the number of total cells, neutrophils, and macrophages in BALF, attenuates histologic lung alterations, decreases the wet-to-dry weight ratio in BALF, and inhibits the activation of NF-kappa-B inhibitor alpha, extracellular regulated protein kinases, c-JunN-terminal kinase, and p38 mitogen-activated protein kinase.