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View larger CBL0137 hydrochloride
AT4361
CAS 1197397-89-9
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $16.65 | Total: $1,665.00 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 5 | $31.45 | Total: $157.25 |
Data sheet
| Molecular Formula | C21H25ClN2O2 |
| Molecular Weight | 372.88 |
| CAS Numbers | 1197397-89-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CC(C)NCCn1c2ccc(cc2c2cc(ccc12)C(C)=O)C(C)=O |
| References | Gasparian AV,etal.Curaxins anticancer compounds that simultaneously suppress NF-?B and activate p53 by targeting FACT.Sci Transl Med. 2011 Aug 10;3[95] 95ra74. |
More info
CBL0137 hydrochloride (Curaxin-137 hydrochloride) activates p53 and inhibits NF-kB (EC50: 0.370.47 ?M) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.