p53

Tenovin-6 Hydrochloride View larger

Tenovin-6 Hydrochloride

AT8480

CAS 1011301-29-3

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$28.00

$28.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.60 Total: $1,260.00
150 $14.56 Total: $728.00
125 $17.08 Total: $427.00
110 $20.16 Total: $201.60
15 $23.80 Total: $119.00

Data sheet

Molecular FormulaC25H35ClN4O2S
Molecular Weight491.09
CAS Numbers1011301-29-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.CN(C)CCCCC(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(C)(C)C)cc1
ReferencesDai W, et al. Class III-specific HDAC inhibitor Tenovin-6 induces apoptosis, suppresses migration and eliminates cancer stem cells in uveal melanoma. Sci Rep. 2016 Mar 4;6 22622.

More info

Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 ?M, 10 ?M, and 67 ?M for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator .