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PF-4708671
AOB5417
CAS No:1255517-76-0
Chemical Name: 2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $4.05 | Total: $405.00 |
| 1 | 50 | $4.68 | Total: $234.00 |
| 1 | 25 | $5.49 | Total: $137.25 |
| 1 | 10 | $6.48 | Total: $64.80 |
| 1 | 5 | $7.65 | Total: $38.25 |
Data sheet
| Molecular Formula | C19H21F3N6 |
| Molecular Weight | 390.41 |
| CAS Numbers | 1255517-76-0 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Synonym | PF4708671; PF-4708671; PF 4708671. |
| IUPAC/Chemical Name | Name: 2-((4-(5-ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole |
| InChl Key | FBLPQCAQRNSVHB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H21F3N6/c1-2-13-10-23-12-24-18(13)28-7-5-27(6-8-28)11-17-25-15-4-3-14(19(20,21)22)9-16(15)26-17/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,25,26) |
| SMILES Code | FC(C1=CC=C2NC(CN3CCN(C4=NC=NC=C4CC)CC3)=NC2=C1)(F)F |
| References | 1) Leontieva OV, Demidenko ZN, Blagosklonny MV. S6K in geroconversion. Cell Cycle. 2013 Oct 15;12(20):3249-52. doi: 10.4161/cc.26248. Epub 2013 Sep 9. PubMed PMID: 24036549. 2) Allard EK, Grujic M, Fisone G, Kristensson K. Prion formation correlates with activation of translation-regulating protein 4E-BP and neuronal transcription factor Elk1. Neurobiol Dis. 2013 Oct;58:116-22. doi: 10.1016/j.nbd.2013.05.014. Epub 2013 Jun 3. PubMed PMID: 23742760. |
More info
The first highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)