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AOB5267
CAS: 213971-34-7
Chemical Name: FX-11; 7-Benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $22.05 | Total: $2,205.00 |
1 | 50 | $25.48 | Total: $1,274.00 |
1 | 25 | $29.89 | Total: $747.25 |
1 | 10 | $35.28 | Total: $352.80 |
1 | 5 | $41.65 | Total: $208.25 |
Molecular Formula | C22H22O4 |
Molecular Weight | 350.41 |
CAS Numbers | 213971-34-7 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | FX 11; FX-11; FX11 |
IUPAC/Chemical Name | 7-Benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid |
InChl Key | LVPYVYFMCKYFCZ-UHFFFAOYSA-N |
InChl Code | InChI=1S/C22H22O4/c1-3-7-16-17-10-13(2)15(11-14-8-5-4-6-9-14)12-18(17)19(22(25)26)21(24)20(16)23/h4-6,8-10,12,23-24H,3,7,11H2,1-2H3,(H,25,26) |
SMILES Code | O=C(C1=C2C=C(CC3=CC=CC=C3)C(C)=CC2=C(CCC)C(O)=C1O)O |
References | 1) He Y, et al. LDHA is a direct target of miR-30d-5p and contributes to aggressive progression of gallbladder carcinoma. Mol Carcinog. 2018 Mar 23. 2) Rellinger EJ, Craig BT, Alvarez AL, Dusek HL, Kim KW, Qiao J, Chung DH. FX11 inhibits aerobic glycolysis and growth of neuroblastoma cells. Surgery. 2017 Mar;161(3):747-752. 3) Yang J, Wang C, Zhao F, Luo X, Qin M, Arunachalam E, Ge Z, Wang N, Deng X, Jin G, Cong W, Qin W. Loss of FBP1 facilitates aggressive features of hepatocellular carcinoma cells through the Warburg effect. Carcinogenesis. 2017 Feb 1;38(2):134-143 |
Selective inhibitor of LDHA, inhibiting tumor xenograft progression