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Fluorofenidone
AOB36003
CAS: 848353-85-5
Chemical Name: 3-Fluorofenidone; AKF-PD; 1-(3-Fluorophenyl)-5-methylpyridin-2-one
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $11.25 | Total: $1,125.00 |
| 1 | 50 | $13.00 | Total: $650.00 |
| 1 | 25 | $15.25 | Total: $381.25 |
| 1 | 10 | $18.00 | Total: $180.00 |
| 1 | 5 | $21.25 | Total: $106.25 |
Data sheet
| Molecular Formula | C12H10FNO |
| Molecular Weight | 203.22 |
| CAS Numbers | 848353-85-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Fluorofenidone |
| IUPAC/Chemical Name | 1-(3-Fluorophenyl)-5-methylpyridin-2-one |
| InChl Key | JDZYVVUJIQYGRX-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C12H10FNO/c1-9-5-6-12(15)14(8-9)11-4-2-3-10(13)7-11/h2-8H,1H3 |
| SMILES Code | O=C1C=CC(C)=CN1C2=CC=CC(F)=C2 |
| References | 1) Tang J, et Spermidine-mediated poly(lactic-co-glycolic acid) nanoparticles containing fluorofenidone for the treatment of idiopathic pulmonary fibrosis. Int J Nanomedicine. 2017 Sep 8;12:6687-6704. 2) Deng ZH, et. Fluorofenidone Inhibits the Proliferation of Lung Adenocarcinoma Cells. J Cancer. 2017 Jul 4;8(10):1917-1926. 3) Xiong SQ, Jiang HB, Xu HZ, Xia XB. Effect of pyridone agent on blood-retinal barrier in diabetic mice. Int J Ophthalmol. 2017 Jun 18;10(6):890-895. |
More info
Novel antifibrotic and anti-inflammatory agent, restoring caveolin 1 expression and inhibiting mitogen-activated protein kinase signaling pathway, also inhibiting phosphorylation of extracellular signal-regulated kinase, P38, and c-Jun N-terminal kinase