Pathway Inhibitors

Autogramin-2 View larger

Autogramin-2

AOB13195

CAS: 2375541-45-8

Chemical Name: tert-Butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

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$15.00

$15.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $6.75 Total: $675.00
50 $7.80 Total: $390.00
25 $9.15 Total: $228.75
10 $10.80 Total: $108.00
5 $12.75 Total: $63.75

Data sheet

Molecular FormulaC21H27N3O4S
Molecular Weight417.52
CAS Numbers2375541-45-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Nametert-Butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
InChl KeyPNSFNXURLSDVRV-UHFFFAOYSA-N
InChl CodeInChI=1S/C21H27N3O4S/c1-13(2)27-15-8-6-14(7-9-15)18(25)23-19-22-16-10-11-24(12-17(16)29-19)20(26)28-21(3,4)5/h6-9,13H,10-12H2,1-5H3,(H,22,23,25)
SMILES CodeO=C(NC1=NC(CCN(C(OC(C)(C)C)=O)C2)=C2S1)C3=CC=C(OC(C)C)C=C3
ReferencesLaraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.

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Novel autophagy inhibitor, selectively targeting cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A), and directly competing with cholesterol binding to the GRAMD1A StART domain