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AOB36416
CAS: 1019158-02-1
Chemical Name: 2-(4-Methoxyphenyl)-1-((5-(2-nitrophenyl)furan-2-yl)methyl)pyrrolidine
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $9.45 | Total: $945.00 |
1 | 50 | $10.92 | Total: $546.00 |
1 | 25 | $12.81 | Total: $320.25 |
1 | 10 | $15.12 | Total: $151.20 |
1 | 5 | $17.85 | Total: $89.25 |
Molecular Formula | C22H22N2O4 |
Molecular Weight | 378.43 |
CAS Numbers | 1019158-02-1 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | i-ST2-1; iST2 1; iST2-1 |
IUPAC/Chemical Name | 2-(4-Methoxyphenyl)-1-((5-(2-nitrophenyl)furan-2-yl)methyl)pyrrolidine |
InChl Key | RBVNERPDMZVXIP-UHFFFAOYSA-N |
InChl Code | InChI=1S/C22H22N2O4/c1-27-17-10-8-16(9-11-17)20-7-4-14-23(20)15-18-12-13-22(28-18)19-5-2-3-6-21(19)24(25)26/h2-3,5-6,8-13,20H,4,7,14-15H2,1H3 |
SMILES Code | O=[N+](C1=CC=CC=C1C2=CC=C(CN3C(C4=CC=C(OC)C=C4)CCC3)O2)[O-] |
References | Ramadan AM, Daguindau E, Rech JC, Chinnaswamy K, Zhang J, Hura GL, Griesenauer B, Bolten Z, Robida A, Larsen M, Stuckey JA, Yang CY, Paczesny S. From proteomics to discovery of first-in-class ST2 inhibitors active in vivo. JCI Insight. 2018 Jul 25;3(14). pii: 99208. doi: 10.1172/jci.insight.99208. [Epub ahead of print] PubMed PMID: 30046004; PubMed Central PMCID: PMC6124397. |
First-in-class ST2 inhibitor active in vivo