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View larger GSK046 (iBET-BD2)
AOB11458
CAS: 2474876-09-8
Chemical Name: GSK046; 4-Acetamido-3-fluoro-N-((1r,4S)-4-hydroxycyclohexyl)-5-((S)-1-phenylethoxy)benzamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Data sheet
| Molecular Formula | C23H27FN2O4 |
| Molecular Weight | 414.48 |
| CAS Numbers | 2474876-09-8 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 95% by HPLC |
| Synonym | iBET BD2; iBET-BD2; iBETBD2; GSK-046; GSK 046 |
| IUPAC/Chemical Name | 4-Acetamido-3-fluoro-N-((1r,4S)-4-hydroxycyclohexyl)-5-((S)-1-phenylethoxy)benzamide |
| SMILES Code | O=C(N[C@H]1CC[C@H](O)CC1)C2=CC(O[C@H](C3=CC=CC=C3)C)=C(NC(C)=O)C(F)=C2 |
| References | 1) Omer G, et, al. Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation. Science. 2020 Apr 24; 368(6489): 387-394. |
More info
Novel potent BD2-selective inhibitor with 1000-fold selectivity over BD1
