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View larger AOB31453
CAS: 92285-87-5
Chemical Name: 4-Chloro-5-{2-[(3-hydroxyphenyl)methylidene]hydrazin-1-yl}-2,3-dihydropyridazin-3-one
1865 Items
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.88 | Total: $159.38 |
| 1 | 10 | $27.00 | Total: $270.00 |
| 1 | 25 | $22.88 | Total: $571.88 |
| 1 | 50 | $19.50 | Total: $975.00 |
| 1 | 100 | $16.88 | Total: $1,687.50 |
| Molecular Formula | C11H9ClN4O2 |
| Molecular Weight | 264.67 |
| CAS Numbers | 92285-87-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | L82-G17; L82G17; L82 G17 |
| IUPAC/Chemical Name | 4-Chloro-5-{2-[(3-hydroxyphenyl)methylidene]hydrazin-1-yl}-2,3-dihydropyridazin-3-one |
| InChl Key | PYYWVUBALUMAIY-WLRTZDKTSA-N |
| InChl Code | InChI=1S/C11H9ClN4O2/c12-10-9(6-14-16-11(10)18)15-13-5-7-2-1-3-8(17)4-7/h1-6,17H,(H2,15,16,18)/b13-5+ |
| SMILES Code | O=C1C(Cl)=C(N/N=C/C2=CC=CC(O)=C2)C=NN1 |
| References | 1) Howes TRL, Sallmyr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. DNA Repair (Amst). 2017 Dec;60:29-39. doi: 10.1016/j.dnarep.2017.10.002. Epub 2017 Oct 10. Erratum in: DNA Repair (Amst). 2017 Dec 19;:. PubMed PMID: 29078112; PubMed Central PMCID: PMC5881949. |
Novel selective uncompetitive inhibitor of DNA ligase I (LigI)