Pathway Inhibitors

L82-G17 View larger

L82-G17

AOB31453

CAS: 92285-87-5

 

Chemical Name: 4-Chloro-5-{2-[(3-hydroxyphenyl)methylidene]hydrazin-1-yl}-2,3-dihydropyridazin-3-one

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$37.50

$37.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.88 Total: $1,687.50
150 $19.50 Total: $975.00
125 $22.88 Total: $571.88
110 $27.00 Total: $270.00
15 $31.88 Total: $159.38

Data sheet

Molecular FormulaC11H9ClN4O2
Molecular Weight264.67
CAS Numbers92285-87-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymL82-G17; L82G17; L82 G17
IUPAC/Chemical Name4-Chloro-5-{2-[(3-hydroxyphenyl)methylidene]hydrazin-1-yl}-2,3-dihydropyridazin-3-one
InChl KeyPYYWVUBALUMAIY-WLRTZDKTSA-N
InChl CodeInChI=1S/C11H9ClN4O2/c12-10-9(6-14-16-11(10)18)15-13-5-7-2-1-3-8(17)4-7/h1-6,17H,(H2,15,16,18)/b13-5+
SMILES CodeO=C1C(Cl)=C(N/N=C/C2=CC=CC(O)=C2)C=NN1
References1) Howes TRL, Sallmyr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. DNA Repair (Amst). 2017 Dec;60:29-39. doi: 10.1016/j.dnarep.2017.10.002. Epub 2017 Oct 10. Erratum in: DNA Repair (Amst). 2017 Dec 19;:. PubMed PMID: 29078112; PubMed Central PMCID: PMC5881949.

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Novel selective uncompetitive inhibitor of DNA ligase I (LigI)

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