Pathway Inhibitors

cjoc42 View larger

cjoc42

AOB9643

CAS: N/A

 

Chemical Name: Methyl 4-(4-(3-(tosyloxy)propyl)-1H-1,2,3-triazol-1-yl)benzoate

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$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.15 Total: $1,215.00
150 $14.04 Total: $702.00
125 $16.47 Total: $411.75
110 $19.44 Total: $194.40
15 $22.95 Total: $114.75

Data sheet

Molecular FormulaC20H21N3O5S
Molecular Weight415.46
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymCJOC42; CJOC-42; CJOC 42;
IUPAC/Chemical NameMethyl 4-(4-(3-(tosyloxy)propyl)-1H-1,2,3-triazol-1-yl)benzoate
InChl KeyVYUDJPGSULLWAS-UHFFFAOYSA-N
InChl CodeInChI=1S/C20H21N3O5S/c1-15-5-11-19(12-6-15)29(25,26)28-13-3-4-17-14-23(22-21-17)18-9-7-16(8-10-18)20(24)27-2/h5-12,14H,3-4,13H2,1-2H3
SMILES CodeO=C(OC)C1=CC=C(N2N=NC(CCCOS(=O)(C3=CC=C(C)C=C3)=O)=C2)C=C1
References1) Anasuya Chattopadhyay, et al., Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell, Scientific Reports volume 6, Article number: 23732 (2016)

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Novel inhibitor of the oncoprotein gankyrin, preventing the decrease in p53 protein levels associated with high amounts of gankyrin, restoring p53-dependent transcription and sensitivity to DNA damage






























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