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View larger AOB9643
CAS: N/A
Chemical Name: Methyl 4-(4-(3-(tosyloxy)propyl)-1H-1,2,3-triazol-1-yl)benzoate
970 Items
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.95 | Total: $114.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 100 | $12.15 | Total: $1,215.00 |
| Molecular Formula | C20H21N3O5S |
| Molecular Weight | 415.46 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | CJOC42; CJOC-42; CJOC 42; |
| IUPAC/Chemical Name | Methyl 4-(4-(3-(tosyloxy)propyl)-1H-1,2,3-triazol-1-yl)benzoate |
| InChl Key | VYUDJPGSULLWAS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H21N3O5S/c1-15-5-11-19(12-6-15)29(25,26)28-13-3-4-17-14-23(22-21-17)18-9-7-16(8-10-18)20(24)27-2/h5-12,14H,3-4,13H2,1-2H3 |
| SMILES Code | O=C(OC)C1=CC=C(N2N=NC(CCCOS(=O)(C3=CC=C(C)C=C3)=O)=C2)C=C1 |
| References | 1) Anasuya Chattopadhyay, et al., Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell, Scientific Reports volume 6, Article number: 23732 (2016) |
Novel inhibitor of the oncoprotein gankyrin, preventing the decrease in p53 protein levels associated with high amounts of gankyrin, restoring p53-dependent transcription and sensitivity to DNA damage