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Pelitrexol

AOB446022339

CAS: 446022-33-9

 

Chemical Name: (S)-2-(5-(2-((S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl)ethyl)-4-methylthiophene-2-carboxamido)pentanedioic acid

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$119.00

$119.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $101.15 Total: $505.75
110 $85.68 Total: $856.80
125 $72.59 Total: $1,814.75
150 $61.88 Total: $3,094.00
1100 $53.55 Total: $5,355.00

Data sheet

Molecular FormulaC20H25N5O6S
Molecular Weight463.51
CAS Numbers446022-33-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity 99% (HPLC)
SynonymAG-2037; AG 2037; AG2037; Pelitrexol.
IUPAC/Chemical Name (S)-2-(5-(2-((S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl)ethyl)-4-methylthiophene-2-carboxamido)pentanedioic acid
InChl KeyQXOPTIPQEVJERB-JQWIXIFHSA-N
InChl CodeInChI=1S/C20H25N5O6S/c1-9-6-14(18(29)23-12(19(30)31)3-5-15(26)27)32-13(9)4-2-10-7-11-16(22-8-10)24-20(21)25-17(11)28/h6,10,12H,2-5,7-8H2,1H3,(H,23,29)(H,26,27)(H,30,31)(H4,21,22,24,25,28)/t10-,12-/m0/s1
SMILES CodeO=C(O)[C@@H](NC(C1=CC(C)=C(CC[C@H](CN2)CC3=C2N=C(N)NC3=O)S1)=O)CCC(O)=O
References1) Frost, Gregory I.; Jiang, Ping; Thompson, Curtis B. Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions. PCT Int. Appl. (2009), 292 pp. CODEN: PIXXD2 WO 2009128917 A2 20091022 CAN 151:462825 AN 2009:1297488

2) Czarnik, Anthony W. Deuterium-enriched pelitrexol. U.S. Pat. Appl. Publ. (2009), 10pp. CODEN: USXXCO US 2009062316 A1 20090305 CAN 150:314122 AN 2009:270615

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A GARFT inhibitor that has a water soluble antifolate with anti-proliferative activity.