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View larger Miclxin
AOB11572
CAS: 2494198-61-5
Chemical Name: DS37262926; 7-Methoxy-N-(3-methoxybenzyl)-2-(3-(pyridin-3-yl)pyrrolidin-1-yl)quinazolin-4-amine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $58.65 | Total: $293.25 |
| 1 | 10 | $49.68 | Total: $496.80 |
| 1 | 25 | $42.09 | Total: $1,052.25 |
| 1 | 50 | $35.88 | Total: $1,794.00 |
| 1 | 100 | $31.05 | Total: $3,105.00 |
Data sheet
| Molecular Formula | C26H27N5O2 |
| Molecular Weight | 441.54 |
| CAS Numbers | 2494198-61-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | BD01288232 |
| IUPAC/Chemical Name | 7-Methoxy-N-(3-methoxybenzyl)-2-(3-(pyridin-3-yl)pyrrolidin-1-yl)quinazolin-4-amine |
| InChl Key | OXSWPFXQCLRTCF-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C26H27N5O2/c1-32-21-7-3-5-18(13-21)15-28-25-23-9-8-22(33-2)14-24(23)29-26(30-25)31-12-10-20(17-31)19-6-4-11-27-16-19/h3-9,11,13-14,16,20H,10,12,15,17H2,1-2H3,(H,28,29,30) |
| SMILES Code | COC1=CC2=C(C=C1)C(=NC(=N2)N3CCC(C3)C4=CN=CC=C4)NCC5=CC(=CC=C5)OC |
| References | 1) Hiroaki Ikeda et al., Miclxin, a Novel MIC60 Inhibitor, Induces Apoptosis via Mitochondrial Stress in β-Catenin Mutant Tumor Cells, ACS Chem. Biol. 2020, 15, 8, 2195–2204 |
| PubChem ID | 155891739 |
More info
Novel MIC60 Inhibitor, Inducing Apoptosis via Mitochondrial Stress in β-Catenin Mutant Tumor Cells