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DCH36_06
AOB17776
CAS: 593273-05-3
Chemical Name: 1-(3-Chloro-4-methylphenyl)-5-(3-(furan-2-yl)allylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity (mg or Unit) | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|
| 100 | $35.55 | Total: $3,555.00 |
| 50 | $41.08 | Total: $2,054.00 |
| 25 | $48.19 | Total: $1,204.75 |
| 10 | $56.88 | Total: $568.80 |
| 5 | $67.15 | Total: $335.75 |
Data sheet
| Molecular Formula | C18H13ClN2O3S |
| Molecular Weight | 372.82 |
| CAS Numbers | 593273-05-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | DCH36_06; DCH36 06; DCH36-06; DCH 36-06; DCH36-06; DCH-36-06; DCH 3606; DCH-3606; DCH3606; |
| IUPAC/Chemical Name | 1-(3-Chloro-4-methylphenyl)-5-(3-(furan-2-yl)allylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione |
| InChl Key | AYNCXNUUERDREH-FMDPHQNASA-N |
| InChl Code | InChI=1S/C18H13ClN2O3S/c1-11-7-8-12(10-15(11)19)21-17(23)14(16(22)20-18(21)25)6-2-4-13-5-3-9-24-13/h2-10H,1H3,(H,20,22,25)/b4-2+,14-6+ |
| SMILES Code | O=C(/C(C(N1C2=CC=C(C)C(Cl)=C2)=O)=CC=CC3=CC=CO3)NC1=S |
| References | 1) Lu W, Xiong H, Chen Y, Wang C, Zhang H, Xu P, Han J, Xiao S, Ding H, Chen Z, Lu T, Wang J, Zhang Y, Yue L, Liu YC, Zhang C, Yang Y, Jiang H, Chen K, Zhou B, Luo C. Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors. Bioorg Med Chem. 2018 Nov 1;26(20):5397-5407. doi: 10.1016/j.bmc.2018.07.048. Epub 2018 Jul 27. PubMed PMID: 30297119. |
More info
Novel potent p300/CBP inhibitor, showing potent anti-proliferation as well as anti-tumor activity in leukemia xenograft