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MEISi-1
AOB11439
CAS: 446306-43-0
Chemical Name: 4-(2-(Benzylamino)-2-oxoethoxy)-N-(2,3-dimethylphenyl)benzamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $35.55 | Total: $3,555.00 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 5 | $67.15 | Total: $335.75 |
Data sheet
| Molecular Formula | C24H24N2O3 |
| Molecular Weight | 388.47 |
| CAS Numbers | 446306-43-0 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| Synonym | MEISi-1; MEISi 1; MEISi1 |
| IUPAC/Chemical Name | 4-(2-(Benzylamino)-2-oxoethoxy)-N-(2,3-dimethylphenyl)benzamide |
| InChl Key | MNJQVNZAPZMEDA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H24N2O3/c1-17-7-6-10-22(18(17)2)26-24(28)20-11-13-21(14-12-20)29-16-23(27)25-15-19-8-4-3-5-9-19/h3-14H,15-16H2,1-2H3,(H,25,27)(H,26,28) |
| SMILES Code | O=C(NC1=CC=CC(C)=C1C)C2=CC=C(OCC(NCC3=CC=CC=C3)=O)C=C2 |
| References | 1) Turan RD, Albayrak E, Uslu M, Siyah P, Alyazici LY, Kalkan BM, Aslan GS, Yucel D, Aksoz M, Tuysuz EC, Meric N, Durdagi S, Gulbas Z, Kocabas F. Development of Small Molecule MEIS Inhibitors that modulate HSC activity. Sci Rep. 2020 May 14;10(1):7994. doi: 10.1038/s41598-020-64888-3. PMID: 32409701; PMCID: PMC7224207. |
More info
Novel MEIS inhibitor (MEISi), significantly inhibiting MEIS-luciferase reporters in vitro and inducing murine (LSKCD34low cells) and human (CD34+, CD133+, and ALDHhi cells) HSC self-renewal ex vivo