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View larger NCI126224
AOB1372
CAS 65974-52-9
Chemical Name: NCI-126224; 2-(2-Nitro-benzylidene)-malonic acid dimethyl ester
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Data sheet
| Molecular Formula | C12H11NO6 |
| Molecular Weight | 265.22 |
| CAS Numbers | 65974-52-9 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | NCI-126224; NCI 126224 |
| IUPAC/Chemical Name | Dimethyl 2-(2-Nitrobenzylidene)Malonate |
| InChl Key | LKLMASCOTOBEMT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C12H11NO6/c1-18-11(14)9(12(15)19-2)7-8-5-3-4-6-10(8)13(16)17/h3-7H,1-2H3 |
| SMILES Code | COC(=O)C(=CC1=CC=CC=C1[N+](=O)[O-])C(=O)OC |
| References | 1) Shuting Zhang et al., Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors. Bioorg Med Chem. 2012 Oct 15;20(20):6073-9. doi: 10.1016/j.bmc.2012.08.022. Epub 2012 Aug 25. |
| PubChem ID | 277385 |
More info
TLR4 signaling inhibitor, suppressing LPS-induced production of NF-κB, TNF-α, IL-1β, and NO