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View larger SZL-P1-41
AOB2911
CAS No: 222716-34-9
Chemical Name: 3-(2-Benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one; SKP2 E3 Ligase Inhibitor III
AOBIOUS launched this product in 2016
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| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Data sheet
| Molecular Formula | C24H24N2O3S |
| Molecular Weight | 420.52 |
| CAS Numbers | 222716-34-9 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-(2-benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one |
| InChl Key | JKIXLEKBXHMXTN-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H24N2O3S/c1-2-15-12-16-22(28)18(24-25-19-8-4-5-9-20(19)30-24)14-29-23(16)17(21(15)27)13-26-10-6-3-7-11-26/h4-5,8-9,12,14,27H,2-3,6-7,10-11,13H2,1H3 |
| SMILES Code | O=C1C(C2=NC3=C(C=CC=C3)S2)=COC4=C1C=C(CC)C(O)=C4CN5CCCCC5 |
| References | 1) Chan, C.H., Morrow, J.K., Li, C.F., et al. Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell. 154(3), 556-568 (2013). |
More info
Novel Skp2 inhibitor, selectively suppressing Skp2 SCF E3 ligase activity
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