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Brincidofovir View larger

Brincidofovir

AOB37050

CAS 444805-28-1

Chemical Name: P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-phosphonic acid, mono[3-(hexadecyloxy)propyl] ester

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$17.50

$17.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $14.88 Total: $74.38
110 $12.60 Total: $126.00
125 $10.68 Total: $266.88
150 $9.10 Total: $455.00
1100 $7.88 Total: $787.50

Data sheet

Molecular FormulaC27H52N3O7P
Molecular Weight561.7
CAS Numbers444805-28-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC
SynonymHexadecyloxypropyl-CDV; 1-O-hexadecyloxypropyl Cidofovir; CMX001; HDP-CDV; HDP (S)-HPMPC
IUPAC/Chemical NameP-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-phosphonic acid, mono[3-(hexadecyloxy)propyl] ester
InChl KeyWXJFKKQWPMNTIM-VWLOTQADSA-N
InChl CodeInChI=1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)/t25-/m0/s1
SMILES CodeO=P(OCCCOCCCCCCCCCCCCCCCC)(O)CO[C@H](CO)CN1C(N=C(C=C1)N)=O
References1) Aldern, K.A., Ciesla, S.L., Winegarden, K.L., et al. Increased antiviral activity of 1-O-hexadecyloxypropyl-[2-14C]cidofovir in MRC-5 human lung fibroblasts is explained by unique cellular uptake and metabolism. Mol. Pharmacol. 63(3), 678-681 (2003).

2) Quenelle, D.C., Collins, D.J., Wan, W.B., et al. Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir. Antimicrob. Agents Chemother. 48(2), 404-412 (2004).

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Prodrug of cidofovir for the treatment of Ebola virus disease