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MRTX849 (Adagrasib)
AOB11360
CAS 2326521-71-3
Chemical Name: 2-((S)-4-(7-(8-chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $26.55 | Total: $2,655.00 |
| 1 | 50 | $30.68 | Total: $1,534.00 |
| 1 | 25 | $35.99 | Total: $899.75 |
| 1 | 10 | $42.48 | Total: $424.80 |
| 1 | 5 | $50.15 | Total: $250.75 |
Data sheet
| Molecular Formula | C32H35ClFN7O2 |
| Molecular Weight | 604.13 |
| CAS Numbers | 2326521-71-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | MRTX849; MRTX-849; MRTX 849; Adagrasib; |
| IUPAC/Chemical Name | 2-((S)-4-(7-(8-chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile |
| InChl Key | PEMUGDMSUDYLHU-ZEQRLZLVSA-N |
| InChl Code | InChI=1S/C32H35ClFN7O2/c1-21(34)31(42)41-17-16-40(18-23(41)11-13-35)30-25-12-15-39(28-10-4-7-22-6-3-9-26(33)29(22)28)19-27(25)36-32(37-30)43-20-24-8-5-14-38(24)2/h3-4,6-7,9-10,23-24H,1,5,8,11-12,14-20H2,2H3/t23-,24-/m0/s1 |
| SMILES Code | O=C(C(F)=C)N([C@@H](CC#N)C1)CCN1C2=NC(OC[C@H]3N(C)CCC3)=NC4=C2CCN(C5=CC=CC6=C5C(Cl)=CC=C6)C4 |
More info
Novel covalent inhibitor of KRASG12C