Pathway Inhibitors

YE6144 View larger

YE6144

AOB16858

CAS: N/A

 Chemical Name: (S,E)-N1-(6-Fluoro-3-(2-(6-morpholinopyridazin-3-yl)vinyl)-1H-indazol-5-yl)butane-1,2-diamine hydrochloride

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$219.00

$219.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $98.55 Total: $9,855.00
150 $113.88 Total: $5,694.00
125 $133.59 Total: $3,339.75
110 $157.68 Total: $1,576.80
15 $186.15 Total: $930.75

Data sheet

Molecular FormulaC21H27ClFN7O
Molecular Weight447.94
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name(S,E)-N1-(6-Fluoro-3-(2-(6-morpholinopyridazin-3-yl)vinyl)-1H-indazol-5-yl)butane-1,2-diamine hydrochloride
SMILES CodeCC[C@@H](CNC1=CC2=C(NN=C2/C=C/C3=CC=C(N4CCOCC4)N=N3)C=C1F)N.[H]Cl
References1) Ban T, et al. Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease. Nat Commun. 2021 Jul 19;12(1):4379.

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Novel selective IRF5 inhibitor, inhibiting the phosphorylation of IRF5 in both human PBMCs and mouse splenocytes