Pathway Inhibitors

PSB-CB-27 View larger

PSB-CB-27

AOB19004

CAS: 2237222-16-9

 

Chemical Name: PBPO; PBTO; (4aS,10bS)-4-Propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol Hydrochloride

More details

Molarity Calculation Cart®

HOW TO ORDER

$63.40

$63.40 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $28.53 Total: $2,853.00
150 $32.97 Total: $1,648.40
125 $38.67 Total: $966.85
110 $45.65 Total: $456.48
15 $53.89 Total: $269.45

Data sheet

Molecular FormulaC25H27ClN2O3S
Molecular Weight471.012
CAS Numbers2237222-16-9
Storage Condition0°C (short term), -20°C (long term), desiccated
Purity 99% (HPLC)
IUPAC/Chemical Name(Z)-2-(3-((5-(4-chlorophenoxy)pentyl)oxy)benzylidene)-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3(2H)-one
InChl KeyDLCUOANMQWMLPN-XLNRJJMWSA-N
InChl CodeInChI=1S/C24H25ClN2O3S/c25-19-8-10-20(11-9-19)29-13-2-1-3-14-30-21-7-4-6-18(16-21)17-22-23(28)27-12-5-15-31-24(27)26-22/h4,6-11,16-17H,1-3,5,12-15H2/b22-17-
SMILES CodeO=C(N(CCCS1)C1=N/2)C2=CC3=CC(OCCCCCOC4=CC=C(Cl)C=C4)=CC=C3
References1) Schoeder CT, et al. Eur J Med Chem. 2018 Jul 15;155:381-397.

2) Kozłowska H, et al. Int J Mol Sci. 2022 Jan 26;23(3):1427.

More info

Novel selective antagonist of GPR18, exhibiting a pIC50 of 6.2 at the hGPR18 in the β-arrestin recruitment assays