Pathway Inhibitors

(2S)-2'-Methoxykurarinone View larger

(2S)-2'-Methoxykurarinone

ATN1215

CAS 270249-38-2

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$49.00

$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.05 Total: $2,205.00
150 $25.48 Total: $1,274.00
125 $29.89 Total: $747.25
110 $35.28 Total: $352.80
15 $41.65 Total: $208.25

Data sheet

Molecular FormulaC27H32O6
Molecular Weight452.54
CAS Numbers270249-38-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cc(O)ccc1[C@@H]1CC(=O)c2c(OC)cc(O)c(C[C@@H](CC=C(C)C)C(C)=C)c2O1
ReferencesSasaki T, et al. Protein tyrosine phosphatase 1B inhibitory activity of lavandulyl flavonoids from roots of Sophora flavescens. Planta Med. 2014 May;80[7] 557-60.

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(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone displays cytotoxic activity against human myeloid leukemia HL-60 cells.