Pathway Inhibitors

(-)-Butin View larger

(-)-Butin

ATN1461

CAS 492-14-8

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$57.00

$57.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $25.65 Total: $2,565.00
150 $29.64 Total: $1,482.00
125 $34.77 Total: $869.25
110 $41.04 Total: $410.40
15 $48.45 Total: $242.25

Data sheet

Molecular FormulaC15H12O5
Molecular Weight272.25
CAS Numbers492-14-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOc1ccc2C(=O)C[C@H](Oc2c1)c1ccc(O)c(O)c1
ReferencesThe cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3KAktNrf2-dependent pathway.J Cell Biochem. 2012 Jun;113[6] 1987-97.

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(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SOD induction via the PI3KAkt signaling pathway.