Cart 0 Product Products (empty)
No products
Free shipping! Shipping
$0.00 Total
Product successfully added to your shopping cart
Quantity
Unit
Total
There are 0 items in your cart. There is 1 item in your cart.
Total products (tax excl.)
Total shipping (tax excl.) Free shipping!
Total (tax excl.)
Pathway Inhibitors
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- PROTAC Linker
- SARS-CoV
View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $103.05 | Total: $10,305.00 |
| 1 | 50 | $119.08 | Total: $5,954.00 |
| 1 | 25 | $139.69 | Total: $3,492.25 |
| 1 | 10 | $164.88 | Total: $1,648.80 |
| 1 | 5 | $194.65 | Total: $973.25 |
Data sheet
| Molecular Formula | C31H43ClN4O5 |
| Molecular Weight | 587.15 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.COc1cccc(CN([C@H]2C[C@H](N(Cc3ccc4OCOc4c3)C2)C(=O)N2CCNCC2)C(=O)CC(C)(C)C)c1 |
| References | Juliet A Williams, et al. Identification of a small molecule inhibitor of the hedgehog signaling pathway effects on basal cell carcinoma-like lesions. Proc Natl Acad Sci U S A. 2003 Apr 15;100[8] 4616-21. |
More info
CUR61414 hydrochloride is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM). CUR61414 hydrochloride is a small-molecule aminoproline class compound. CUR61414 hydrochloride selectively binds to smoothened (Smo, Ki= 44 nM). CUR61414 hydrochloride can induce cancer cells apoptosis without affecting neighboring non-tumor cells.