Pathway Inhibitors

A-443654 View larger

A-443654

AT14072

CAS 552325-16-3

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$71.00

$71.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $31.95 Total: $3,195.00
150 $36.92 Total: $1,846.00
125 $43.31 Total: $1,082.75
110 $51.12 Total: $511.20
15 $60.35 Total: $301.75

Data sheet

Molecular FormulaC24H23N5O
Molecular Weight397.47
CAS Numbers552325-16-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC([C@@H](COC=1C=C(C=NC1)C=2C=C3C(=CC2)NN=C3C)N)C=4C=5C(NC4)=CC=CC5
ReferencesLuo Y, et al. Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo. Mol Cancer Ther. 2005 Jun;4[6] 977-86.

More info

A-443654, a pan-Akt inhibitor, exhibits equal potency against Akt1, Akt2, and Akt3 within cells (Ki=160 pM).