Pathway Inhibitors

JW 67 View larger

JW 67

AT22884

CAS 442644-28-2

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$32.00

$32.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.40 Total: $1,440.00
150 $16.64 Total: $832.00
125 $19.52 Total: $488.00
110 $23.04 Total: $230.40
15 $27.20 Total: $136.00

Data sheet

Molecular FormulaC21H18N2O6
Molecular Weight394.38
CAS Numbers442644-28-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1Nc2ccccc2C11OCC2(CO1)COC1(OC2)C(=O)Nc2ccccc12
ReferencesWaaler J, et al. Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth. Cancer Res. 2011;71[1] 197-205.

More info

JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active ?-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.