Pathway Inhibitors

HhAntag View larger

HhAntag

AT3460

CAS 496794-70-8

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$54.00

$54.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $24.30 Total: $2,430.00
150 $28.08 Total: $1,404.00
125 $32.94 Total: $823.50
110 $38.88 Total: $388.80
15 $45.90 Total: $229.50

Data sheet

Molecular FormulaC24H23ClN4O3
Molecular Weight450.92
CAS Numbers496794-70-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cc(OC)cc(c1)C(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(ccc2[nH]1)N(C)C
ReferencesActis, Marcelo; Connelly, Michele C.; Mayasundari, Anand et al. A structure-activity relationship study of small-molecule inhibitors of GLI1-mediated transcription. Biopolymers [2011], 95[1], 24-30.

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HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity.