Pathway Inhibitors

2,5-dimethyl Celecoxib View larger

2,5-dimethyl Celecoxib

AT35610

CAS 457639-26-8

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$46.00

$46.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $20.70 Total: $2,070.00
150 $23.92 Total: $1,196.00
125 $28.06 Total: $701.50
110 $33.12 Total: $331.20
15 $39.10 Total: $195.50

Data sheet

Molecular FormulaC18H16F3N3O2S
Molecular Weight395.4
CAS Numbers457639-26-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1=CC(C2=CC(=NN2C2=CC=C(C=C2)S(N)(=O)=O)C(F)(F)F)=C(C)C=C1
ReferencesMajchrzak-Celi?ska A, et al. COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt?-catenin pathway and COX-2PGE2EP4 signaling in glioblastoma cells. BMC Cancer. 2021 May 3;21[1] 493.

More info

2,5-dimethyl Celecoxib is a celecoxib derivative and a targeted inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), a key enzyme in the PGE2 synthesis pathway of inflammatory mediators.