Pathway Inhibitors

GDC-0449 View larger

GDC-0449 (Vismodegib)

CTY2449

CAS No:879085-55-9

Chemical Name: Vismodegib

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$9.00

$9.00 per mg

Must order minimum 5 quantity for this product.

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.05 Total: $405.00
150 $4.68 Total: $234.00
125 $5.49 Total: $137.25
110 $6.48 Total: $64.80
15 $7.65 Total: $38.25

Data sheet

Molecular FormulaC19H14Cl2N2O3S
Molecular Weight421.3
CAS Numbers879085-55-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity 99% (HPLC)

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An orally-administered small molecule inhibitor of Hedgehog

References:

1. Amini S, Viera MH, Valins W, Berman B. Nonsurgical innovations in the treatment of nonmelanoma skin cancer. J Clin Aesthet Dermatol. 2010 Jun;3(6):20-34.
2. So PL, Tang JY, Epstein EH. Novel investigational drugs for basal cell carcinoma. Expert Opin Investig Drugs. 2010 Sep;19(9):1099-112.
3. De Smaele E, Ferretti E, Gulino A. Vismodegib, a small-molecule inhibitor of the hedgehog pathway for the treatment of advanced cancers. Curr Opin Investig Drugs. 2010 Jun;11(6):707-18.