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View larger SAG dihydrochloride
AT40465
CAS 2702366-44-5
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $42.50 | Total: $212.50 |
| 1 | 10 | $36.00 | Total: $360.00 |
| 1 | 25 | $30.50 | Total: $762.50 |
| 1 | 50 | $26.00 | Total: $1,300.00 |
| 1 | 100 | $22.50 | Total: $2,250.00 |
Data sheet
| Molecular Formula | C28H30Cl3N3OS |
| Molecular Weight | 562.98 |
| CAS Numbers | 2702366-44-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C1=C(C2=CC=CC=C2S1)Cl)N([C@@H]3CC[C@H](CC3)NC)CC4=CC(C5=CC=NC=C5)=CC=C4.Cl.Cl |
| References | Chen JK, et al. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A. 2002 Oct 29;99[22] 14071-6. |
More info
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.