Pathway Inhibitors

GDC-0980 View larger

GDC-0980

AOB87742

CAS No:1032754-93-0

Chemical Name: RG7422 

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$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular FormulaC23H30N8O3S
Molecular Weight498.6
CAS Numbers1032754-93-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity 99% (HPLC)

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A potent, selective dual inhibitor of class I PI3K and mTOR kinase

References:

1. A. J. Wangner, et al, Mol Cancer Ther, Dec. 2009, Vol 8, Issue 12, Suppl. 1
2. D. P. Sutherlin, et al., Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer, J. Med. Chem., 2011, 54 (21), pp 7579–7587