Pathway Inhibitors

ZW4864 free base View larger

ZW4864 free base

AT9642

CAS 2632259-92-6

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$139.00

$139.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $62.55 Total: $6,255.00
150 $72.28 Total: $3,614.00
125 $84.79 Total: $2,119.75
110 $100.08 Total: $1,000.80
15 $118.15 Total: $590.75

Data sheet

Molecular FormulaC33H42N6O3
Molecular Weight570.72
CAS Numbers2632259-92-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1
ReferencesWang Z, et al. Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the ?-CateninB-Cell Lymphoma 9 Protein-Protein Interaction. J Med Chem. 2021;64[16] 12109-12131.

More info

ZW4864 (free base) is an orally active and selective ?-cateninB-Cell lymphoma 9 protein-protein interaction (?-cateninBCL9 PPI) inhibitor, with a K_i value of 0.76 ?M and an IC_50 value of 0.87 ?M [1]. ZW4864 (free base) also demonstrates good pharmacokinetic properties.