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Pathway Inhibitors
- Protein Control Ligand
- Pathway Inhibitors
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View larger ZW4864 free base
AT9642
CAS 2632259-92-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $118.15 | Total: $590.75 |
| 1 | 10 | $100.08 | Total: $1,000.80 |
| 1 | 25 | $84.79 | Total: $2,119.75 |
| 1 | 50 | $72.28 | Total: $3,614.00 |
| 1 | 100 | $62.55 | Total: $6,255.00 |
Data sheet
| Molecular Formula | C33H42N6O3 |
| Molecular Weight | 570.72 |
| CAS Numbers | 2632259-92-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |
| References | Wang Z, et al. Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the ?-CateninB-Cell Lymphoma 9 Protein-Protein Interaction. J Med Chem. 2021;64[16] 12109-12131. |
More info
ZW4864 (free base) is an orally active and selective ?-cateninB-Cell lymphoma 9 protein-protein interaction (?-cateninBCL9 PPI) inhibitor, with a K_i value of 0.76 ?M and an IC_50 value of 0.87 ?M [1]. ZW4864 (free base) also demonstrates good pharmacokinetic properties.