Pathway Inhibitors

S1QEL1.1 View larger

S1QEL1.1

AOBS1948

CAS No: 897613-29-5  

Chemical Name: N1-(3-acetamidophenyl)-N2-(2-(4-methyl-2-(p-tolyl)thiazol-5-yl)ethyl)oxalamide, S1QEL

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$29.50

$29.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.28 Total: $1,327.50
150 $15.34 Total: $767.00
125 $18.00 Total: $449.88
110 $21.24 Total: $212.40
15 $25.08 Total: $125.38

Data sheet

Molecular FormulaC23H24N4O3S
Molecular Weight436.53
CAS Numbers897613-29-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSA: 2 mg/mL
Purity98% by HPLC

More info

A suppressor of mitochondrial respiratory complex I site IQ electron leak, suppressing superoxide and/or H2O2 production without altering oxidative phosphorylation. S1QEL1.1 had an IC50 values of 70 nM against superoxide-H2O2 production from site IQ. It decreased caspase activation in a in a cardiomyocyte cell model of ER stress and decreased ischemia-reperfusion injury in the Langendorff-perfused mouse heart model.