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> Pathway Inhibitors>Enzyme Inhibitors>Peptidase>Y-29794 Tosylate

Peptidase

Y-29794 Tosylate View larger

Y-29794 Tosylate

AOB8370

CAS: 143984-17-2

 

Chemical Name: (2-((8-(Dimethylamino)octyl)thio)-6-isopropylpyridin-3-yl)(thiophen-2-yl)methanone Tosylate

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $21.25 Total: $106.25
110 $18.00 Total: $180.00
125 $15.25 Total: $381.25
150 $13.00 Total: $650.00
1100 $11.25 Total: $1,125.00

Data sheet

Molecular FormulaC30H42N2O4S3
Molecular Weight590.86
CAS Numbers143984-17-2 (tosylate)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymY 29794; Y-29794; Y29794; Y29794 tosylate; Y-29794 tosylate; Y 29794 tosylate.
IUPAC/Chemical Name(2-((8-(dimethylamino)octyl)thio)-6-isopropylpyridin-3-yl)(thiophen-2-yl)methanone 4-methylbenzenesulfonate
SMILES CodeCC(C1=CC=C(C(C2=CC=CS2)=O)C(SCCCCCCCCN(C)C)=N1)C.CC3=CC=C(S(=O)(O)=O)C=C3
References1) Kato A, Fukunari A, Sakai Y, Nakajima T. Prevention of amyloid-like deposition by a selective prolyl endopeptidase inhibitor, Y-29794, in senescence-accelerated mouse. J Pharmacol Exp Ther. 1997 Oct;283(1):328-35. PubMed PMID: 9336340.

2) Nakajima T, Ono Y, Kato A, Maeda J, Ohe T. Y-29794--a non-peptide prolyl endopeptidase inhibitor that can penetrate into the brain. Neurosci Lett. 1992 Jul 20;141(2):156-60. PubMed PMID: 1436628.

More info

Orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor