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Teneligliptin HBr
AOB19095
CAS 906093-29-6
Chemical Name: [(2S,4S)-4-[4-(5-Methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone Hydrobromide
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Data sheet
| Molecular Formula | C44H67N12O3S2 |
| Molecular Weight | 1275.74 |
| CAS Numbers | 906093-29-6 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Teneligliptin Hydrobromide |
| IUPAC/Chemical Name | [(2S,4S)-4-[4-(5-Methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone Hydrobromide |
| SMILES Code | CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.Br.Br.Br.Br.Br |
| References | 1) Imazu M, Nakano A, Ito S, Hamasaki T, Kitakaze M; TOPLEVEL investigators and study coordinators. Effects of Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus in Open-Label, Marker-Stratified Randomized, Parallel-Group Comparison, Standard Treatment-Controlled Multicenter Trial (TOPLEVEL Study): Rationale and Study Design. Cardiovasc Drugs Ther. 2019 Mar 9. doi: 10.1007/s10557-019-06871-3. [Epub ahead of print] PubMed PMID: 30850916. |
More info
Long-acting, orally-bioavailable inhibitor of dipeptidyl peptidase-4 (DPP-4), with hypoglycemic activity.