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> Pathway Inhibitors>Enzyme Inhibitors>Peptidase>ML270 (VU0359595)

Peptidase

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ML270 (VU0359595)

AOB1035

CAS No: 1246303-14-9

 

Chemical Name: (1R,2R)-N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-2phenylcyclopropane-1-carboxamide; CID-53361951; VU0359595

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $26.35 Total: $131.75
110 $22.32 Total: $223.20
125 $18.91 Total: $472.75
150 $16.12 Total: $806.00
1100 $13.95 Total: $1,395.00

Data sheet

Molecular FormulaC25H29BrN4O2
Molecular Weight497.43
CAS Numbers1246303-14-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Stock Solution Guide10 mM/4.97 mg/ 1 mL Solvent
Purity98% by HPLC
SynonymML-270, ML 270, ML270, VU0359595, VU-0359595, VU 0359595, CID-53361951, CID53361951, CID 53361951
IUPAC/Chemical Name(1R,2R)-N-[(1S)-2-[4-(5-bromo-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-phenyl-cyclopropanecarboxamide; (1S,2S)-N-[(1S)-2-[4-(5-bromo-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-phenyl-cyclopropanecarboxamide
InChl KeyZJJZIOCVJFWBFM-QDZXWRQZSA-N
InChl CodeInChI=1S/2C25H29BrN4O2/c2*1-16(27-24(31)21-14-20(21)17-5-3-2-4-6-17)15-29-11-9-19(10-12-29)30-23-8-7-18(26)13-22(23)28-25(30)32/h2*2-8,13,16,19-21H,9-12,14-15H2,1H3,(H,27,31)(H,28,32)/t16-,20+,21-;16-,20-,21+/m00/s1
SMILES CodeO=C([C@H]1[C@H](C2=CC=CC=C2)C1)N[C@@H](C)CN3CCC(N4C5=CC=C(Br)C=C5NC4=O)CC3
References1) Lewis, J.A., Scott, S.A., Lavieri, R., et al. Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity. Bioorg. Med. Chem. Lett. 19(7), 1916-1920 (2009).

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Potent and selective phospholipase D1inhibitor