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> Activators>Potassium Channel>ML111 (VU590 HCl)

Potassium Channel

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ML111 (VU590 HCl)

AOB1540

CAS No: 1783987-83-6, 313505-85-0 (Free Base)

Chemical Name: 7,13-Bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane dihydrochloride; VU 590

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QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $16.15 Total: $80.75
110 $13.68 Total: $136.80
125 $11.59 Total: $289.75
150 $9.88 Total: $494.00
1100 $8.55 Total: $855.00

Data sheet

Molecular FormulaC24H32N4O7.2HCl
Molecular Weight561.46
CAS Numbers1783987-83-6; 313505-85-0 (Free Base)
Storage Condition-20°C
Solubility100 mM in DMSO
SynonymVU 590 2HCl
IUPAC/Chemical Name7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacyclopentadecane, dihydrochloride
InChl KeyFRYYSUBAHIUBNJ-UHFFFAOYSA-N
InChl CodeInChI=1S/C24H32N4O7.2ClH/c29-27(30)23-5-1-21(2-6-23)19-25-9-13-33-14-10-26(12-16-35-18-17-34-15-11-25)20-22-3-7-24(8-4-22)28(31)32;;/h1-8H,9-20H2;2*1H
SMILES CodeO=[N+](C(C=C1)=CC=C1CN2CCOCCOCCN(CCOCC2)CC3=CC=C([N+]([O-])=O)C=C3)[O-].Cl.Cl
References1) Hebert, S.C., Desir, G., Giebisch, G., et al. Molecular diversity and regulation of renal potassium channels. Physiol. Rev. 85(1), 319-371 (2005).

2) Edwards, A.O. Clinical features of the congenital vitreoretinopathies. Eye (Lond) 22(10), 1233-1242 (2008).

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Inhibitor of ROMK and Kir7.1