Potentiators

PF-04958242 View larger

Pesampator (PF-04958242)

AOB31968

CAS: 1258963-59-5

Chemical Name: N-{(3S,4S)-4-[4-(5-Cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide

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$39.00

$39.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.55 Total: $1,755.00
150 $20.28 Total: $1,014.00
125 $23.79 Total: $594.75
110 $28.08 Total: $280.80
15 $33.15 Total: $165.75

Data sheet

Molecular FormulaC30H35N7O
Molecular Weight509.66
CAS Numbers1258963-59-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC
SynonymBIIB-104; PF-04958242; PF 04958242; PF04958242
IUPAC/Chemical NameN-{(3S,4S)-4-[4-(5-Cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide
InChl KeyTTYKUKSFWHEBLI-DLBZAZTESA-N
InChl Code InChI=1S/C18H20N2O4S2/c1-12(2)26(21,22)20-16-10-23-11-17(16)24-14-5-3-13(4-6-14)18-8-7-15(9-19)25-18/h3-8,12,16-17,20H,10-11H2,1-2H3/t16-,17+/m0/s1
SMILES CodeCC(S(=O)(N[C@H]1COC[C@H]1OC2=CC=C(C3=CC=C(C#N)S3)C=C2)=O)C
References1) Shaffer CL, et al. The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242). J Med Chem. 2015 May 28;58(10):4291-308. doi: 10.1021/acs.jmedchem.5b00300

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Novel potent, selective, and metabolic stable AMPA receptor potentiator

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