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AOB31311
CAS: 519187-97-4
Chemical Name: Edonerpic maleate; 1-{3-[2-(1-Benzothiophen-5-yl) ethoxy]propyl} azetidin-3-ol maleate
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $6.75 | Total: $675.00 |
1 | 50 | $7.80 | Total: $390.00 |
1 | 25 | $9.15 | Total: $228.75 |
1 | 10 | $10.80 | Total: $108.00 |
1 | 5 | $12.75 | Total: $63.75 |
Molecular Formula | C20H25NO6S |
Molecular Weight | 407.48 |
CAS Numbers | 519187-97-4 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | T-817 maleate; T-817; T 817; T817; J2.179.155E; T-817MA; Edonerpic; Edonerpic maleate |
IUPAC/Chemical Name | 1-(3-(2-(benzo[b]thiophen-5-yl)ethoxy)propyl)azetidin-3-ol maleate |
InChl Key | RLUCYBFCLXANSO-BTJKTKAUSA-N |
InChl Code | InChI=1S/C16H21NO2S.C4H4O4/c18-15-11-17(12-15)6-1-7-19-8-4-13-2-3-16-14(10-13)5-9-20-16;5-3(6)1-2-4(7)8/h2-3,5,9-10,15,18H,1,4,6-8,11-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1- |
SMILES Code | OC1CN(CCCOCCC2=CC=C3C(C=CS3)=C2)C1.O=C(O)/C=CC(O)=O |
References | 1) Page SJ, Murray C, Hermann V, Levine P. Retention of motor changes in chronic stroke survivors who were administered mental practice. Arch Phys Med Rehabil. 2011 Nov;92(11):1741-5. 2) Moreno H, Choi S, Yu E, Brusco J, Avila J, Moreira JE, Sugimori M, Llinás RR. Blocking Effects of Human Tau on Squid Giant Synapse Transmission and Its Prevention by T-817 MA. Front Synaptic Neurosci. 2011 May 17;3:3. 3: Kawasaki T, Ago Y, Kitao T, Nashida T, Takagi A, Takuma K, Matsuda T. A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. Neuropharmacology. 2008 Oct;55(5):654-60 |
Novel neuroprotective agent, enhancing cognitive function and restoring parvalbumin-positive γ-aminobutyric acid neurons in the prefrontal cortex and hippocampus