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TAK700
AOB5917
CAS No:426219-18-3
Chemical Name: Orteronel; 6-[7-Hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide
AOBIOUS launched this product in 2015
CITATIONS - Publications That Use AOBIOUS Product
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $13.05 | Total: $1,305.00 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 5 | $24.65 | Total: $123.25 |
Data sheet
| Molecular Formula | C18H17N3O2 |
| Molecular Weight | 307.35 |
| CAS Numbers | 426219-18-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | TAK700; TAK-700; TAK 700; Orteronel; Orteronel racemic mixture. |
| IUPAC/Chemical Name | 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide |
| InChl Key | OZPFIJIOIVJZMN-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H17N3O2/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21/h2-5,8-11,23H,6-7H2,1H3,(H,19,22) |
| SMILES Code | O=C(NC)C1=CC=C2C=C(C3(O)CCN4C=NC=C43)C=CC2=C1 |
| References | 1) Zainuddin M, et al. Preclinical assessment of Orteronel(®), a CYP17A1 enzyme inhibitor in rats. Eur J Drug Metab Pharmacokinet. 2016 Feb;41(1):1-7. doi: 10.1007/s13318-014-0229-2. PubMed PMID: 25297456. 2: Goto A, Moriya Y, Takeuchi T, Mandai T, Tagawa Y, Kondo T, Asahi S. Pharmacokinetics and Urinary Excretion Mechanism of Orteronel (TAK-700), A Novel 17,20-Lyase Inhibitor, in Animals. Drug Res (Stuttg). 2016 Apr;66(4):217-22. doi: 10.1055/s-0035-1564118. PubMed PMID: 26418412. |
More info
Androgen synthesis inhibitor, selectively inhibiting the enzyme CYP17A1